"Tick, Tick, Boom!" brings you conversations with world-renowned researchers and medical professionals to unravel the mysterious link between tick bites and allergic reactions to mammalian products such as beef and pork. This journey begins with one doctor's discovery in a small group of people in Sydney, Australia, and extends to implications in vaccine development, cancer treatment, and a revolutionary change in our understanding of how allergies work.

 

EPISODE 3:

EXPLORING TICK MYTHS AND REALITIES IN AUSTRALIA.

EPISODE 3: EXPLORING TICK MYTHS AND REALITIES IN AUSTRALIA.

A fascinating history of tick research.

Stephen Doggett sheds light on the complex interplay between environmental conditions and tick activity, providing listeners with a comprehensive understanding of the factors that influence tick populations..

EPISODE 3 - Exploring tick myths & realities in australia with entomologist stephen doggett

 Join us as we sit down with Stephen Doggett, a leading medical entomologist from Sydney, to explore the fascinating world of ticks. Stephen shares his journey from a nature-loving child to a renowned expert on ticks, discussing their ability to cause severe allergic reactions and paralysis. Learn about the proteins and toxins ticks inject during bites and how environmental changes have influenced tick populations. Discover why tick-borne diseases are rare in Australia and how urban landscaping has increased tick habitats. Stephen provides practical advice on protective measures, from suitable clothing to effective repellents, and emphasizes the importance of the “Freeze, Don’t Squeeze” method for tick removal.

REFERENCES:

https://onlinelibrary.wiley.com/doi/abs/10.1111/aen.12496

https://static1.squarespace.com/static/5c8ecc0db2cf79dee4986f00/t/6631a58343e1223ce9b18ed4/1714529670552/TickRepellentStudy.pdf

TRANSCRIPT:

Episode #3

Credits:

JANELLE WILLIAMS: EXECUTIVE PRODUCER

REMY WILLIAMS & ZAC STRITCH-HODDLE: PRODUCERS

WEEDITPODCASTS.COM: EDITING


EPISODE 2:

BEYOND THE BITE: EXPLORING AUTOIMMUNE BREAKTHROUGHS AT THE GARVAN INSTITUTE.

EPISODE 2: BEYOND THE BITE: EXPLORING AUTOIMMUNE BREAKTHROUGHS AT THE GARVAN INSTITUTE.

Genetic and molecular insights into dangerous tick bite-related meat allergy revealed.

Providing a framework for future therapeutics development, not only for tick-induced allergies but for other diseases as well.

EPISODE 2 - BEYOND THE BITE: EXPLORING AUTOIMMUNE BREAKTHROUGHS AT THE GARVAN INSTITUTE

In this episode, we speak with Professors Antony Basten and Daniel Christ, as well as Dr David Langley at the Garvan Institute in Sydney, Australia. Where they guide us through the research being done on the alpha-gal molecule and why the Garvan Institute is so interested in understanding it. We talk about everything from how an understanding of alpha-gal could help us better prevent diseases such as malaria, to how tick-induced sensitisation to alpha-gal is associated with increased risk of coronary artery disease.

REFERENCES:

Genetic and structural basis of the human anti-α-galactosyl antibody response

TRANSCRIPT:

Episode #2

Credits:

JANELLE WILLIAMS: EXECUTIVE PRODUCER

REMY WILLIAMS & ZAC STRITCH-HODDLE: PRODUCERS

WEEDITPODCASTS.COM: EDITING


EPISODE 1

UNRAVELLING THE MYSTERIES OF ALPHA-GAL ALLERGIES.

EPISODE 1 UNRAVELLING THE MYSTERIES OF ALPHA-GAL ALLERGIES.

Professor Sheryl van Nunen

First described the association between tick bites and the subsequent development of mammalian meat anaphylaxis, documented the first instance of a proven IgE-mediated mechanism in anaphylaxis to a food (mammalian meat) in systemic mastocytosis and first described ticks as an insect causing anaphylaxis in systemic mastocytosis.

We speak with Professor Sheryl van Nunen to unravel the mystery behind a startling association: a history of tick bites and the subsequent onset of often life-threatening allergic reactions to a sugar known as alpha-gal found in mammalian products such as beef, dairy, and pork. Professor Sheryl van Nunen guides us through the early days of this novel allergy's discovery and the impact this has had on the world. We'll also explore how mammalian meat allergy is unique — it's both preventable and potentially curable. How, you ask? By preventing tick bites and safely removing ticks if you do get bitten. With Professor Sheryl van Nunen's science-backed strategies, this can be easily achieved.

references:

An association between tick bite reactions and red meat allergy in humans

A novel Australian tick Ixodes (Endopalpiger) australiensis inducing mammalian meat allergy after tick bite

Tick killing in situ before removal to prevent allergic and anaphylactic reactions in humans: a cross-sectional study

Immunoglobulin E Sensitization to Mammalian Oligosaccharide Galactose-α-1,3 (α-Gal) Is Associated With Noncalcified Plaque, Obstructive Coronary Artery Disease, and ST-Segment–Elevated Myocardial Infarction

transcript:

Episode #1

Credits:

JANELLE WILLIAMS: EXECUTIVE PRODUCER

REMY WILLIAMS & ZAC STRITCH-HODDLE: PRODUCERS

WEEDITPODCASTS.COM: EDITING

“Remember Freeze it, Don’t Squeeze it”